Absence of CD59

Decay-accelerating factor

Decay-accelerating
Complement decay-accelerating factor also known as CD55 is a protein that, in humans, is encoded by the CD55 gene. Decay accelerating factor is a 70 kDa membrane protein that regulates the complement system on the cell surface. It prevents the assembly of the C3bBb complex or accelerates the disassembly of preformed convertase, thus blocking the formation of the membrane attack complex. This glycoprotein is broadly distributed among hematopoietic and non-hematopoietic cells. It is a determinant for the Cromer blood group system.

Absence of CD59 - List of case studies

PANCYTOPENIA OF UNKNOWN PATHOGENESIS

 74-year-old female evaluated for pancytopenia of unknown etiology, which required blood transfusions. Bone marrow ... with flow cytometries looking for the absence of CD55 and the absence of CD59 on granulocytes since this patient is heavily transfused. In addition, ...

Pancytopenia of uncertain pathogenesis

74-year-old female evaluated for pancytopenia of unknown etiology, which required blood transfusions. Bone marrow aspirate ... hemoglobinuria with flow cytometries looking for the absence of CD55 and the absence of CD59 on granulocytes since this patient is ...

List of Diseases and Conditions

Below is a full list of the diseases and conditions mentioned in case studies throughout the site. ... Abnormalities of the small nerve fibers Abortion Absence of CD55 Absence of CD59 Abundant secretions (thick mucus) Accelerated venous drainage ...

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