DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
C-met inhibitors
C-Met
c-Met (MET or MNNG HOS Transforming gene) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). The hepatocyte growth factor receptor protein possesses tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. MET is a membrane receptor that is essential for embryonic development and wound healing. Hepatocyte growth factor (HGF) is the only known ligand of the MET receptor...
C-met inhibitors - List of case studies
- Papillary Carcinoma of Thyroid with Multiple and Diffuse Nodular Secondarisms of the Pulmonary Parenchyma
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activity in PTC with oral angiogenesis/multikinase inhibitors , such as AMG 706 (Sherman, NEJM, 2008) and sorafenib ... in other targeted therapies, such as mTOR inhibitors or c-met inhibitors , however there is no published clinical data to date on ...
- Treatments
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ABOI transplantation ABOI transplants ACE inhibitors ACL reinsertion operation (right knee) APPENDIX REMOVE ... Bypass surgery C C section C-met inhibitors C4-5 fusion C5 inhibitor Eculizumab C5-6 and ...