Carvedilol is a non-selective beta blocker/alpha-1 blocker indicated in the treatment of mild to moderate congestive heart failure (CHF). It is marketed under various trade names including Carvil, Coreg, Dilatrend, Eucardic, and Carloc as a generic drug (as of September 5, 2007 in the U.S.). , and as a controlled-release formulation, marketed in the US as Coreg CR. Carvedilol was discovered by Robert R. Ruffolo, Jr. It has had a significant role in the treatment of Congestive heart failure.