Cyclophosphamide

Cyclophosphamide

Cyclophosphamide
Cyclophosphamide (INN, trade names Endoxan, Cytoxan, Neosar, Procytox, Revimmune), also known as cytophosphane, is a nitrogen mustard alkylating agent, from the oxazophorines group. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. It is used to treat various types of cancer and some autoimmune disorders. It is a "prodrug"; it is converted in the liver to active forms that have chemotherapeutic activity.

Cyclophosphamide - List of case studies

Multiple Myeloma (MM) and Cardiomyopathy

type of treatment (VTD combination), followed by high-dose cyclophosphamide (HDC) and autologous stem cell transplantation. The patient's ... (the VTD combination x3), followed by high-dose cyclophosphamide (HDC) and tandem (double) autologous stem cell ("bone ...

Operated breast cancer with metastases

and axillary lymph nodes removal . Following IV CMF ( Cyclophosphamide , Methotrexate and Fluorouracil ) every 28 days for 6 ... armpit, and then 4 cycles of AC ( Adriamycin and Cyclophosphamide). One year ago, appeared cerebral, hepatic, right ...

Multiple Sclerosis_2

is critical because of cardiac side effects. Cyclophosphamide (Cytoxan) has also been prescribed for severe, ... Natalizumab, Tysabri, Mitoxantrone, Novantrone, Cyclophosphamide, Cytoxan, Corticosteroids, Muscle relaxants, Baclofen, ...

Symptomatic Pancytopenia- Additional opinion

from oral corticosteroids only, followed by oral cyclophosphamide, oral cyclosporine and finally intravenous anti-thymocyte ... Immune suppressive treatment, oral corticosteroids, oral cyclophosphamide, oral cyclosporine, intravenous anti-thymocyte globulin (ATG), ...

Stage 4 Neuroblastoma

On 27 and 28.06 chemotherapy with Vincristine, Cyclophosphamide and Etoposide has been administered. The therapy has been, ...

Drugs

Curcumin Cyclophoshamide Cyclophospamide Cyclophosphamide Cyclosporine Cyclosporine A Cymbalta ... Oral angiogenesis Oral corticosteroids Oral cyclophosphamide Oral cyclosporine Oral dicumarolics Oral enzyme ...

Thrombotic thrombocytopenic purpura (TTP) secondary to Systemic Lupus Erythematosus (SLE)

ADAMTS13 protein. Immunotherapy such as rituximab, cyclophosphamide, and corticosteroids generally do not work quickly enough to ...

3-year old boy with Medulloblastoma

HD-VP16 (etoposide) 2.4 g/m 2 HD-EDX (cyclophosphamide) 4 g/m 2 CBDCA 1 (carboplatin) 800 mg/m 2 ...

Motor Neuropathy

cortisone,  intravenous ceftriaxone , cyclophosphamide , azathioppirne , methotrexate . ... cortisone,  intravenous ceftriaxone , cyclophosphamide , azathioppirne , methotrexate . ...

IgG Multiple Myeloma

intermediate dose dexamethasone, and continuous low-dose cyclophosphamide is active as well – note that antiviral prophylaxis ... dexamethasone and continuous low-dose oral cyclophosphamide for relapsed multiple myeloma. Br J Haematol 2007; 138:330. ...

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