DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
EGFR inhibitors
Epidermal growth factor receptor
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer. Epidermal Growth Factor was discovered by Stanley Cohen of Vanderbilt University along with Rita Levi-Montalcini for which both received the Nobel prize in Physiology or Medicine in 1986.
EGFR inhibitors - List of case studies
- Treatments
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ABOI transplantation ABOI transplants ACE inhibitors ACL reinsertion operation (right knee) APPENDIX REMOVE ... procedure Anti reflux medication Anti-EGFR therapy Anti-HSV antibody Anti-HZV antibody Anti-MM ...
- Drugs
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5-fluorouracil 5FU A ACE inhibitors ACNS 0222 gadolinium texaphyrin ALIMTA ALLORIL ... Duoloxetine Durogesic E E7080 EGFR inhibitors EGFRinhibitors Eculizumab Efexor Efferalgan ...
- Anaplastic Astrocytoma in the left temporal lobe
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L, Wen PY. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology. 2006 Jul ...
- Glioblastoma
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J, Ostrowsky L, Wen PY. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology. 2006 Jul 11;67(1):156-8. ...
- Multirelapse Squamed Carcinoma of the Skin
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death by 2 years with standard therapies. Small molecular inhibitors of the epidermal growth factor receptor (EGFR) may have an impact. We evaluated gefitinib as an induction therapy in a ...