GD2 and GD3

Ganglioside

Ganglioside
Ganglioside is a molecule composed of a glycosphingolipid with one or more sialic acids linked on the sugar chain. The 60+ known gangliosides differ mainly in the position and number of NANA residues. It is a component of the cell plasma membrane that modulates cell signal transduction events. It appears that they concentrate in lipid rafts. They have recently been found to be highly important in immunology. Natural and semisynthetic gangliosides are considered possible therapeutics for neurodegenerative disorders. Gangliosides are more complex glycosphingolipids in which oligosaccharide chains containing N-acetylneuraminic acid (NeuNAc) are attached to a ceramide...

GD2 and GD3 - List of case studies

Drugs

AREDS formulation AREDS formulation of vitamins and minerals ASA ASPIRIN ATACAND PLUS ATG AVASTIN ... Furosemide G G-CSF G-CSF (Neupogen) GD2 and GD3 GM-CSF GRF Gabapentin Gabapentine ...

Melanoma with metastases

tumor. Subsequently, a lymphadenectomy was performed and the patient initiated treatment with interferon A. As a consequence, he ... and GM-CSF. Unconjugated monoclonal antibodies and GD2 and GD3, IL-2 fusion proteins, anti CTLA-4 monoclonal anti-bodies, dendetric cell ...

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