High mitotic index

Cell cycle

Cell
The cell cycle, or cell-division cycle, is the series of events that takes place in a cell leading to its division and duplication (replication). In cells without a nucleus, the cell cycle occurs via a process termed binary fission. In cells with a nucleus, the cell cycle can be divided in two brief periods: interphase—during which the cell grows, accumulating nutrients needed for mitosis and duplicating its DNA—and the mitosis (M) phase, during which the cell splits itself into two distinct cells, often called "daughter cells". The cell-division cycle is a vital process by which a single-celled fertilized egg develops into a mature organism, as well as the process by which hair, skin, blood cells, and some internal organs are renewed.

High mitotic index - List of case studies

Metastatic melanoma stage IIIC

dermis (maximum thickness 5.8 mm). The lesion shows a high mitotic index (61 mitosis x 10 HPF; proliferation index assessed with Mib-1: ...

Melanoma with metastases

in vertical-growth phase, non-ulcerated, with low mitotic index (o mitosis/mm²), with plentiful brisk type lymphocytic ... and the patient was assigned to Arm A (IFN with high intensified doses) , with a protocol schedule of 4 cycles, each ...

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