DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
MTOR inhibitors
Mammalian target of rapamycin
The mammalian target of rapamycin (mTOR) also known as mechanistic target of rapamycin or FK506 binding protein 12-rapamycin associated protein 1 (FRAP1) is a protein which in humans is encoded by the FRAP1 gene. mTOR is a serine/threonine protein kinase that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis, and transcription. mTOR belongs to the phosphatidylinositol 3-kinase-related kinase protein family.
MTOR inhibitors - List of case studies
- Drugs
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5-fluorouracil 5FU A ACE inhibitors ACNS 0222 gadolinium texaphyrin ALIMTA ALLORIL ... M MAGE-3 peptide METOPROLOL MPA MTOR inhibitors MabCampath Magnesium Medicines:interferon ...
- Glioblastoma
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L, Wen PY. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology. 2006 Jul 11;67(1):156-8. ...
- Anaplastic Astrocytoma in the left temporal lobe
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PY. Pilot study of the combination of EGFR and mTOR inhibitors in recurrent malignant gliomas. Neurology. 2006 Jul ...
- Papillary Carcinoma of Thyroid with Multiple and Diffuse Nodular Secondarisms of the Pulmonary Parenchyma
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activity in PTC with oral angiogenesis/multikinase inhibitors , such as AMG 706 (Sherman, NEJM, 2008) and sorafenib ... is also interest in other targeted therapies, such as mTOR inhibitors or c-met inhibitors , however there is no published clinical ...