Melphalan

Melphalan

Melphalan
Melphalan hydrochloride (trade name Alkeran) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents. An alkylating agent adds an alkyl group (CnH2n+1) to DNA. It attaches the alkyl group to the guanine base of DNA, at the number 7 nitrogen atom of the imidazole ring. Otherwise known as L-Phenylalanine Mustard, or L-PAM, melphalan is a phenylalanine derivative of mechlorethamine.

Melphalan - List of case studies

Recurrent metastases in malignant tumor of left forearm

an intensification of therapy (the CCG protocol used melphalan and total body irradiation).   It is unfortunate ... topotecan, Gleevac, depsipetide, Tarceva, pemetrexad, melphalan.   Treatments : chemotherapy, surgery to ...

Multiple Myeloma (MM) and Cardiomyopathy

June and November 2008, consecutively), using high dose melphalan (MEL) for preparation. He then received intensification treatment ... velcade, thalidomide, dexamethasone, cyclophosphamide, melphalan, bisphosphonate zoledroinic acid, ThalDex, revlimid, lenalidomide, ...

Multiple myeloma with renal involvement, bone lesions and Neuropathy

(Turin) who prescribed the following combined treatment Melphalan-Thalidomide-Dexamethasone-Velcade according to the national GIMEMA ... maintenance can include dexamethasone, with or without melphalan or only melphalan. Only if the protein profile increases ...

Drugs

acetate Melatonin Melfalan Mellis Melphalan Memantine Menopur Vial Menopure Mepral ...

IgG Multiple Myeloma

and a modest reduction in the M-component. He received melphalan-based autologous stem cell transplantation, which was complicated by ... the similar bortezomib, thalidomide, decadron (VTD); melphalan, bortezomib, decadron; or doxil, lenalidomide, decadron . A phase ...

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