DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
Paclitaxel
Paclitaxel
Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. It was discovered in a U.S. National Cancer Institute program at the Research Triangle Institute in 1967 when Monroe E. Wall and Mansukh C. Wani isolated it from the bark of the Pacific yew tree, Taxus brevifolia and named it taxol. When it was developed commercially by Bristol-Myers Squibb (BMS) the generic name was changed to paclitaxel and the BMS compound is sold under the trademark TAXOL. In this formulation, paclitaxel is dissolved in Cremophor EL and ethanol, as a delivery agent...
Paclitaxel - List of case studies
- Small Cell Neuroendocrine Tumor of the Cervix – additional opinion
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patients using four courses of chemotherapy with paclitaxel, carboplatin, and etoposide , administered at 3-week intervals followed by three courses (24 weeks) of weekly paclitaxel in patients with objective response or stable disease. 53% had major ...
- Drugs
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inhibitor PRAVA (40 mg) PRRT treatment Paclitaxel Pain control Pain killers Pain medications ... Tauxib Tavor Taxanes Taxol Taxol (Paclitaxel) Taxotere Tegretol Teicoplanin ...
- Adeno Carcinoma of Lung
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reduced dose chemotherapy (either cisplatinum or paclitaxel ). 4) In addition to the above detailed considerations, ... PET-CT scanning. Medicines : cisplatinum, paclitaxel, cisplatinum, pemetrexed, folic acid, vitamin B12. Treatments ...
- Operated breast cancer with metastases
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the cardiac function makes it possible) with associated Paclitaxel until the maximum of response or tolerance, for no longer than 6 ... tolerance has been reached, suspend chemotherapy with Paclitaxel continuing with the maintenance therapy taking Trastuzumab (if the ...
- Papillary Carcinoma of Thyroid with Multiple and Diffuse Nodular Secondarisms of the Pulmonary Parenchyma
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Moreover, chemotherapy for PTC, such as with adriamycin or paclitaxel, tends to cause more symptoms related to the chemotherapy than ... sorafenib, motesanib, sunitinib, abitins, Adriamycin, paclitaxel, oral angiogenesis, multikinase inhibitors, AMG 706 , ...
- Endometrial Cancer
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survival rates of 55% vs. 42%).2 In a subsequent trial, paclitaxel with doxorubicin had a similar outcome to cisplatin with ... The three-drug regimen (doxorubicin, cisplatin, and paclitaxel) with granulocyte colony-stimulating factor , however, was ... (e.g. doxorubicin) or the taxanes [e.g. paclitaxel (Taxol)] to cisplatin increases the response rate. More intensive ...