DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
Platinum drugs
Lipoplatin
Lipoplatin (Liposomal cisplatin) is a nanoparticle of 110 nm average diameter composed of lipids and cisplatin (1). This new drug has successfully finished Phase I, Phase II and Phase III human clinical trials (2,3). It has shown superiority to cisplatin in combination with paclitaxel as a chemotherapy regimen in non-small cell lung cancer (NSCLC) adenocarcinomas. Lipoplatin evades immune surveillance thus escaping clearance from macrophages, circulates for long periods in body fluids after intravenous administration with a half-life of ~120 h, and extravasates through the compromised endothelium of the vasculature in tumors created during the process of neoangiogenesis...
Platinum drugs - List of case studies
- Drugs
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Anti-cholinergic treatment Anti-cholinesterase drugs Anti-coagulation Anti-fibrinolytic agent Anti-hypertensive ... Pipeline Piroxicam Plasil Platinol Platinum Platinum drugs Platinum-based chemotherapy ...
- Multirelapse Squamed Carcinoma of the Skin
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1999: Ischemic cardiopathy and angioplasty Allergy to NAS drugs History : 2003 à removal of a cell-squamed carcinoma ... systemic approaches remaining. I would agree that platinum/5FU/cetuximab as per the EXTREME study is a reasonable approach at ...
- Endometrial Cancer
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benefit for women with advanced endometrial cancer, platinum drugs, anthracyclines and paclitaxel seem the most promising agents. The ...