Rapamycin

Sirolimus

Sirolimus
Sirolimus, also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as Rapa Nui, hence the name. It is marketed under the trade name Rapamune by Wyeth. Sirolimus was originally developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties...

Rapamycin - List of case studies

Diffuse Intra-Axial expansive Lesion of the Enchephalic Trunk

chemotherapies include temozolomide, erlotonib+rapamycin, bevacizumab + CPT-11, and may other common regimens can also be ... (EGFR antibody), chemotherapies, temozolomide, erlotonib, rapamycin, bevacizumab, CPT-11, steroid saving agents, celecoxib, bevacizumab. ...

Drugs

Ramified amino acids Ramipril Ranidil Rapamycin Rate slowing drugs Rebif Rebif (interferon beta 1a) ...

Anaplastic Astrocytoma in the left temporal lobe

Can also consider Tarceva + rapamycin   Doherty L, Gigas DC, Kesari S, Drappatz J, Kim ... temozolomide, Avastin, bevacizumab, irinotecan, Tarceva, rapamycin, EGFR inhibitors, mTOR inhibitors, Gleevec, hydrea, imatinib ... temozolomide, Avastin, bevacizumab, irinotecan, Tarceva, rapamycin, EGFR inhibitors, mTOR inhibitors, Gleevec, hydrea, imatinib ...

Glioblastoma

Can also consider Tarceva + rapamycin Doherty L, Gigas DC, Kesari S, Drappatz J, Kim R, ... , AVASTIN , bevacizumab, Tarceva , rapamycin , irinotecan , EGFR inhibitors , mTOR ... , AVASTIN , bevacizumab, Tarceva , rapamycin , irinotecan , EGFR inhibitors , mTOR ...

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