DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
Salinosporamide
Salinosporamide A
Salinosporamide A is a potent proteasome inhibitor used as an anticancer agent that recently entered phase I human clinical trials for the treatment of multiple myeloma only three years after its discovery. This novel marine natural product is produced by the recently described obligate marine bacterium Salinispora tropica which is found in ocean sediment. Salinosporamide A belongs to a family of compounds possessing a densely functionalized γ-lactam-β-lactone bicycle.
Salinosporamide - List of case studies
- IgG Multiple Myeloma
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include the proteasome inhibitors carfilzomib or salinosporamide ; the new IMID , pomalidomide ; histone deacetylase ... chemotherapy, proteasome inhibitors, carfilzomib, salinosporamide, IMID, pomalidomide, histone deacetylase inhibitors, LAQ824, ... chemotherapy, proteasome inhibitors, carfilzomib, salinosporamide, IMID, pomalidomide, histone deacetylase inhibitors, LAQ824, ...
- Drugs
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S S-1 SIMVASTATIN Salbutamol Salinosporamide Samyr Sandimmun Sandimmun (100 mg) ...