Subtle pulmonary muscle involvement

Myasthenia gravis

Myasthenia
Myasthenia gravis is an autoimmune neuromuscular disease leading to fluctuating muscle weakness and fatiguability. It is an autoimmune disorder, in which weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inhibiting the stimulative effect of the neurotransmitter acetylcholine. Myasthenia is treated medically with cholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy. The disease incidence is 3–30 cases per million and rising as a result of increased awareness...

Subtle pulmonary muscle involvement - List of case studies

Motor Neuron Disease – another opinion

evidence for ALS or neuromuscular junction defect. Pulmonary function tests including routine spirometry as well as maximal ... expiratory pressure testing can be useful to identify subtle pulmonary muscle involvement . Swallowing evaluation may also help delineate the nature ...

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