DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
Temozolomide
Temozolomide
Temozolomide (brand names Temodar and Temodal Schering-Plough Corporation) is an oral alkylating agent which can be used for the treatment of Grade IV astrocytoma — an aggressive brain tumor, also known as glioblastoma multiforme as well as melanoma, a form of skin cancer. It is also indicated for Grade III Anaplastic Astrocytoma and not indicated for, but now used to treat oligodendroglioma brain tumors in some countries, replacing the older (and less well-tolerated) PCV regimen. The agent was developed by Malcolm Stevens and his team at Aston University in Birmingham, A derivative of imidazotetrazine, temozolomide is the prodrug of MTIC (3-methyl-imidazole-4-carboxamide)...
Temozolomide - List of case studies
- Anaplastic Astrocytoma in the left temporal lobe
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Would consider treatment with standard of care drug temozolomide first before moving to more experimental options below: ... Yung WK, Prados MD, et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic ...
- Glioblastoma of the right temporal occipital region
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of chemo-radiation with concurrent treatment with temozolomide (75mg/m2/d) and radiation therapy followed by adjuvant cycles of temozolomide (150-200 mg/m2/d x5 days, q28 days). This treatment should be ...
- Diffuse Intra-Axial expansive Lesion of the Enchephalic Trunk
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more aggressive investigational chemotherapies include temozolomide, erlotonib+rapamycin, bevacizumab + CPT-11, and may other common ... Nexium, Nimotuzumab (EGFR antibody), chemotherapies, temozolomide, erlotonib, rapamycin, bevacizumab, CPT-11, steroid saving agents, ...
- Diffuse Intra-Axial expansive Lesion of the Enchephalic Trunk not surgically investigated_4
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we would proceed with bevacizumab plus or minus temozolomide or irinotecan , either on or off an experimental, clinical trial. ... continuing the nimotuzumab or initiating bevacizumab or temozolomide. (3) Now the young ...
- Relapse of Chondrosarcoma of Cervical Spine
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Successful treatment of a chemoresistant tumor with temozolomide in an adult patient: report of a recurrent intracranial ...
- Diffuse Intra-Axial expansive Lesion of the Enchephalic Trunk not surgically investigated _3
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would recommend outside of a clinical trial oral temozolomide or oral etoposide , or on or off a clinical trial, bevacizumab ... antibiotics, cortisone , chemotherapy , temozolomide (oral), oral etoposide (oral), bevacizumab, irinotecan, ... antibiotics, cortisone , chemotherapy , temozolomide (oral), oral etoposide (oral), bevacizumab, irinotecan, ...
- Drugs
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Telebrix Temodal Temozolomide Temozolomide (oral) Tenormin Teriparatide Tetrabenazine ...
- Metastatic well differentiated neuroendocrine carcinoma in liver
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to high proliferation capacity and the liver metastases, temozolomide in combination with capecitabine might be an option. ... Medicines : oral hypoglycemic, temozolomide, capecitabine. Treatments : surgical ...