DOCTORS'
Medical Case Studies
DOCTORS'
Medical Case Studies
Thalidomide
Thalidomide
Thalidomide was introduced as a sedative drug in the late 1950s and typically used to cure morning sickness. In 1961, it was withdrawn due to teratogenicity and neuropathy. There is now a growing clinical interest in thalidomide, and it is introduced as an immunomodulatory agent used primarily, combined with dexamethasone, to treat multiple myeloma. The drug is a potent teratogen in zebrafish, chickens, rabbits and primates including humans: severe birth defects may result if the drug is taken during pregnancy. Thalidomide was sold in a number of countries across the world from 1957 until 1961 when it was withdrawn from the market after being found to be a cause of birth defects in what has been called "one of the biggest medical tragedies of modern times"...
Thalidomide - List of case studies
- Symptomatic Pancytopenia- Additional opinion
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modalities such as erythropoietin injections, and oral thalidomide. questions: ... too, such as erythropoietin injections , and oral thalidomide . Patients who receive multiple ...
- Multiple Myeloma (MM) and Cardiomyopathy
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type of treatment, including bortezomib (velcade), thalidomide and dexamethasone (the VTD combination x3), followed by high-dose ... of VTD (?), and now receives maintenance (?) based on thalidomide (?, if I understand well). As a supportive treatment he ...
- Pancytopenia of uncertain pathogenesis
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Immune suppression (Globulins / ATG, cyclosporine); Thalidomide; Lenalidomide; Chemotherapy; Decitabine; 5-aza-cytabine – ... (100 mg), Pantorc (20 mg), Erythropoietin , Thalidomide, Lenalidomide , Decitabine , 5-aza-cytabine, ...
- Symptomatic Pancytopenia
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suppression (Globulins / ATG, cyclosporine); Thalidomide; Lenalidomide; Chemotherapy; Decitabine; 5-aza-cytabine ... Immune suppression, Globulins, ATG, cyclosporine, Thalidomide, Lenalidomide, Chemotherapy, Decitabine, 5-aza-cytabine, ...
- Drugs
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Oral progestogens Oral supplements Oral thalidomide Oramorph Orudis Oxaliplatin Oxicontin 20-50 ... Teriparatide Tetrabenazine ThalDex Thalidomide Thalidomide (BMPT) Theophylline Therapeutic ...
- Multiple myeloma with renal involvement, bone lesions and Neuropathy
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who prescribed the following combined treatment Melphalan-Thalidomide-Dexamethasone-Velcade according to the national GIMEMA protocol; ... hydration. After discharge (11/2006) treatment with Thalidomide-Dexamethasone was begun, associated with Clexane, which the ...
- IgG Multiple Myeloma
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with bortezomib and steroids for 6 cycles followed by thalidomide. The disease has responded to therapy. ... to this treatment? 3) What are the next steps when Thalidomide will not be effective and the disease will progress? 4) Future ...
- PANCYTOPENIA OF UNKNOWN ETIOLOGY
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suppression ( Globulins / ATG, cyclosporine ); Thalidomide ; Lenalidomide ; Chemotherapy ; Decitabine ; ... injections, globulins, ATG, thalidomide, lenalidomide, decitabine, 5-aza-cytabine ...