White matter lesions

Pathophysiology of multiple sclerosis

Pathophysiology
Multiple sclerosis is a condition in which the CNS of a person present a special kind of distributed lesions (sclerosis) whose pathophysiology is complex and still under investigation. It is considered a pathological entity by some authors and a clinical entity by some others. At least five characteristics are present in CNS tissues of MS patients: Inflammation beyond classical white matter lesions, Intrathecal Ig production with oligoclonal bands, An environment fostering immune cell persistence, Follicle-like aggregates in the meninges and a disruption of the blood-brain barrier also outside of active lesions...

White matter lesions - List of case studies

Inflammatory Demyelinizing Disease

small hyperintense foci in the long TR sequence at the white matter level of both cerebral hemispheres, numerically prevalent in the left ...

Motor Neuron Disease – another opinion

cerebral atrophy with possible periventricular white matter changes . There were no other intracranial lesions. The actual MRI ...

Motor Neuron Disease

cerebral atrophy with possible periventricular white matter changes . There were no other intracranial lesions. The actual MRI ...

Chronic ischemic brain changes and bilateral carotid atherosclerosis in 89 years old patient

small ischemia foci seemingly of recent origin in the white matter of the radiate crown from the right side.   ...

Multiple Sclerosis_2

cranial nerve deficit. Brain MRI showed at least a dozen white matter lesions, one of them contrast-enhancing. Sensory evoked potentials ...

Cluster headache

of about 1.2 cm, localized in correspondence of the white matter of the right parietal radiate crown , near the cella media of ...

Optic Neuropathy

pallor of the neuro-retinal rim. 10. Are there any white matter lesions seen on the MRI that could be consistent with multiple ...

Demyelinizing Disease

lengthened relaxation time in the temporal periventricular white matter deep bilaterally: finding consistent with demyelinizing disease ...

Motor Neuron Disease – additional opinion

cerebral atrophy with possible periventricular white matter changes . There were no other intracranial lesions. The actual MRI ...

Multiple Sclerosis_1

cranial nerve deficit. Brain MRI showed at least a dozen white matter lesions, one of them contrast-enhancing. Sensory evoked potentials ...

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